Nurse Practitioner salary in Missouri
A nurse practitioner in Missouri earns an estimated $116,200 a year ($55.87/hr) — about 12% below the U.S. average, with most between $98,590 and $123,970. State figures are estimates based on national pay for the role and local cost of living — a starting point, not a guaranteed local wage.
Nurse Practitioner — Missouri
EstimatedMedian annual pay
$116,200
-12% vs nationalHourly
$55.87/hr
- Typical range
- $98,590–$123,970
- What most nurses earn
- High end
- $148,750
- Top earners
- Entry level
- $83,190
- Newer nurses
Nurse Practitioner pay by city in Missouri
Estimated pay in the state's largest metro areas.
| City | Est. annual | Est. hourly |
|---|---|---|
| St. Louis | $118,850 | $57.14 |
| Kansas City | $118,850 | $57.14 |
Nurse Practitioner pay in nearby-paying states
How Missouri compares to states with similar nurse practitioner pay.
Other nursing roles in Missouri
Compare estimated pay for related roles in this state.
What affects nurse practitioner pay in Missouri
Pay below the national median. For a nurse practitioner specifically, pay is shaped by the metro labor market, hospital vs clinic vs long-term-care setting, union presence, shift differentials, unit acuity, and years of experience. Certifications and a move into charge or advanced-practice roles raise pay further. Use the calculator to estimate your own.
How this estimate was calculated
The Missouri figure adjusts the national RN average of $132,050 for local pay levels — a factor of 0.88× (about 12% below the U.S. average). It is a starting point — not an official Missouri wage — until verified local figures and nurse submissions are loaded.
Local pay can vary well beyond this by specialty, shift, union status, employer type, overtime, and care setting. When official state wage data is loaded, this number updates to a verified value automatically.
Use this state estimate as a starting point
- It’s a starting point for Missouri, based on national pay and local cost of living until official state data is loaded — not a guaranteed local wage.
- Your actual pay shifts with role and specialty, care setting, shift, overtime, union status, and years of experience — so compare a role-specific page and personalize the calculator.
- Reviewed salary submissions from nurses in Missouri make this page more precise over time.
Nurse Practitioner salary in Missouri — FAQ
- How much does a nurse practitioner make in Missouri?
- A nurse practitioner in Missouri earns an estimated $116,200 a year — about $55.87 an hour, with most between $98,590 and $123,970. That's about 12% below the national average. This is an estimate based on national pay for the role and Missouri's local pay level, not a guaranteed local wage.
- Is Missouri a good state for nurse practitioners?
- For pay, Missouri sits about 12% below the national average for nurse practitioners. A higher number often comes with a higher cost of living, so weigh the estimated $116,200 against local housing and expenses rather than the headline figure alone.
- Which city in Missouri pays nurse practitioners the most?
- Among Missouri metros we track, St. Louis tends to have the highest estimated pay for nurse practitioners, at roughly $118,850 a year. City figures are estimates based on the role's national pay and local cost of living.
- How does Missouri nurse practitioner pay compare to the national average?
- The national figure for a nurse practitioner is about $132,050 a year, versus an estimated $116,200 in Missouri — about 12% below the national average. Use the calculator to factor in your experience, specialty, and shift.
- Why are some figures verified and others estimates?
- National pay for the main nursing roles — registered nurses, LPNs/LVNs, nurse practitioners, CRNAs, nurse midwives, and nursing assistants — comes from verified public wage data. State, city, and specialty figures that aren't reported on their own start from that national pay and are labeled "Estimated" or "Specialty estimate." We never show an estimate as a verified figure.
Source & confidence— An estimate based on national nurse pay and local cost of living. A ballpark to start from, not an exact figure.
Modeled estimate (BLS national × state wage index)
Missouri figures for SOC 29-1171 are modeled by applying a state wage index of 0.88 to the BLS national median. Import official OEWS state files to replace with verified figures.
Source year 2024. Last reviewed June 1, 2025. Full methodology
Estimated figure — national nurse practitioner pay adjusted for Missouri. Last reviewed June 1, 2025.