Are these South Carolina figures exact?

No — they're modeled estimates, not verified South Carolina wages. They start from each role's national pay and adjust for South Carolina's cost of labor, and they update to verified numbers when official state data is loaded.

Why are some figures verified and others estimates?

National pay for the main nursing roles — registered nurses, LPNs/LVNs, nurse practitioners, CRNAs, nurse midwives, and nursing assistants — comes from verified public wage data. State, city, and specialty figures that aren't reported on their own start from that national pay and are labeled "Estimated" or "Specialty estimate." We never show an estimate as a verified figure.

South Carolina · SC

Nurse Practitioner vs Certified Registered Nurse Anesthetist salary in South Carolina

In South Carolina, certified registered nurse anesthetists earn more — an estimated $208,200 a year versus $116,420 for nurse practitioners, a gap of about $91,780 (roughly 79% more). Both are estimates based on national pay for each role adjusted for South Carolina.

Nurse Practitioner — South Carolina

Estimated

Median annual pay

$116,420

-12% vs national

Hourly

$55.97/hr

Median $116,420

$89,180Middle 50%: $103,830–$137,900$153,490

Typical range: $103,830–$137,900; What most nurses earn
High end: $153,490; Top earners
Entry level: $89,180; Newer nurses

Certified Registered Nurse Anesthetist — South Carolina

Estimated

Median annual pay

$208,200

-12% vs national

Hourly

$100.10/hr

Median $208,200

$136,620Middle 50%: $181,920–$259,030$298,760

Typical range: $181,920–$259,030; What most nurses earn
High end: $298,760; Top earners
Entry level: $136,620; Newer nurses

Why the gap in South Carolina

Both are advanced-practice nurses with graduate degrees. CRNAs (nurse anesthetists) typically out-earn nurse practitioners, reflecting the doctoral anesthesia training, autonomy, and call coverage. The South Carolina figures apply the same local pay adjustment to both roles, so the gap here mirrors the national picture, shifted for South Carolina's cost of labor. Actual pay varies with experience, specialty, shift, and employer — compare the national Nurse Practitioner vs Certified Registered Nurse Anesthetist comparison or personalize the calculator.

Nurse Practitioner vs Certified Registered Nurse Anesthetist in South Carolina — FAQ

Do nurse practitioners or certified registered nurse anesthetists earn more in South Carolina?: In South Carolina, certified registered nurse anesthetists earn more — an estimated $208,200 a year versus $116,420 for nurse practitioners, a gap of about $91,780 (roughly 79% more). Both are estimates based on national pay for each role adjusted for South Carolina's local pay level.
How much is the nurse practitioner vs certified registered nurse anesthetist pay gap in South Carolina?: The estimated gap in South Carolina is about $91,780 a year, or roughly 79% more for certified registered nurse anesthetists. Your actual pay depends on experience, specialty, shift, and employer — use the calculator to compare both for your situation.
Are these South Carolina figures exact?: No — they're modeled estimates, not verified South Carolina wages. They start from each role's national pay and adjust for South Carolina's cost of labor, and they update to verified numbers when official state data is loaded.
Why are some figures verified and others estimates?: National pay for the main nursing roles — registered nurses, LPNs/LVNs, nurse practitioners, CRNAs, nurse midwives, and nursing assistants — comes from verified public wage data. State, city, and specialty figures that aren't reported on their own start from that national pay and are labeled "Estimated" or "Specialty estimate." We never show an estimate as a verified figure.

Source & confidence— An estimate based on national nurse pay and local cost of living. A ballpark to start from, not an exact figure.

Modeled estimate (BLS national × state wage index)

South Carolina figures are estimated by adjusting the U.S. Bureau of Labor Statistics OEWS national median for local pay levels (a state adjustment of 0.88×).

Source year 2025. Last reviewed July 3, 2026. Full methodology

Estimated figures for South Carolina. Last reviewed July 3, 2026.